摘要：
联合注射富血小板纤维蛋白(I-PRF)、白细胞和富血小板纤维蛋白(L-PRF)和生物相容性骨替代材料的引导骨再生(GBR)是一种方便、有效的增强垂直和水平组合骨缺损的方法。
这种方法可以为种植手术部位创造足够的骨质量和数量。一位55岁的亚洲妇女在下颌后部出现严重的骨缺损。无牙颌牙槽嵴垂直和水平吸收严重。
采用I-PRF和L-PRF联合颗粒骨移植进行GBR手术.术后锥束CT扫描，8个月后，显示大面积的牙槽骨再生，足以植入。
联合使用I-PRF/L-PRF和颗粒骨移植可以提供生物活性分子和成骨支架。
这种治疗方案可能是一个可行的选择，一个大的骨缺损需要扩大前植入。
作者：普拉坎河 [1] ; Sirichai，Kiattavorncharoen ; 乔治·R·迪布 ; 索波普湾
作者单位：弗吉尼亚联邦大学23298弗吉尼亚联邦大学北12街520号美国里士满弗吉尼亚联邦大学。 [1]
期刊：
关键词：Gbr;PRF;骨再生;牙种植体;注射型富血小板纤维蛋白
DOI：10.1563/aaid-joi-D-20-00031
PMID：33270878
发布时间：2020-12-03
Guided bone regeneration (GBR) using a combined injectable platelet-rich fibrin (i-PRF), leukocyte- and platelet-rich fibrin (L-PRF) and biocompatible bone substitute materials, is a convenient and effective method to augment a combined vertical and horizontal bone defect.
This approach can create sufficient bone quality and quantity for implant surgical sites. A 55-year-old Asian woman presented with a severe bone defect in posterior mandible.
The edentulous mandibular alveolar ridge was severely resorbed vertically and horizontally.
A GBR procedure using i-PRF and L-PRF combined with particulate bone graft was performed. Postoperative cone beam computed tomography scans, 8 months after the augmentation, revealed a large regeneration of the alveolar bone sufficient for implant placement.
A combination i-PRF/L-PRF and particulate bone graft may provide biologically active molecules as well as a scaffold for osteogenesis.
This treatment protocol may be a viable option for a large bone defect required augmentation prior to implant placement.
作者：Prakan,Thanasrisuebwong [1] ; Sirichai,Kiattavorncharoen ; George R,Deeb ; Sompop,Bencharit
作者单位：Virginia Commonwealth University General Practic 520 North 12th St., UNITED STATES Richmond VA 23298 Virginia Commonwealth University. [1]
期刊：
《The Journal of oral implantology》
关键词：GBR;PRF;bone regeneration;dental implants;injectable platelet-rich fibrin
DOI：10.1563/aaid-joi-D-20-00031
PMID：33270878
发布时间：2020-12-03
